Which diagnostic test is specific for systemic lupus erythematosus?

Which diagnostic test is specific for systemic lupus erythematosus?

• A. Anti-DNA antibody testing
• B. Serum electrolyte levels
• C. Liver function tests
• D. Thyroid function tests

Answer: (A)

The test for anti-DNA antibodies is specifically associated with systemic lupus erythematosus (SLE). These antibodies are directed against double-stranded DNA, which is a hallmark of this autoimmune disease. The presence of anti-DNA antibodies can indicate not only SLE but also help assess the severity of the disease and monitor disease activity. This is essential because the management of SLE often requires a detailed understanding of the individual’s antibody profile. In contrast, serum electrolyte levels, liver function tests, and thyroid function tests are not specific to SLE. While they can provide valuable information about a patient’s overall health and help monitor for complications that may arise due to SLE or its treatment, they are not diagnostic for SLE itself. These tests are more general assessments that can apply to numerous situations and conditions, thus lacking the specificity needed to diagnose systemic lupus erythematosus.

The test for anti-DNA antibodies is specifically associated with systemic lupus erythematosus (SLE). These antibodies are directed against double-stranded DNA, which is a hallmark of this autoimmune disease. The presence of anti-DNA antibodies can indicate not only SLE but also help assess the severity of the disease and monitor disease activity. This is essential because the management of SLE often requires a detailed understanding of the individual’s antibody profile.

In contrast, serum electrolyte levels, liver function tests, and thyroid function tests are not specific to SLE. While they can provide valuable information about a patient’s overall health and help monitor for complications that may arise due to SLE or its treatment, they are not diagnostic for SLE itself. These tests are more general assessments that can apply to numerous situations and conditions, thus lacking the specificity needed to diagnose systemic lupus erythematosus.